PREVENTATIVE POLICIES IN TRANSFUSION-ASSOCIATED GRAFT-VERSUS-HOST DISEASE IN THE TREATMENT OF CANCER

Authors
WEBB DKH
Citation
Dkh. Webb, PREVENTATIVE POLICIES IN TRANSFUSION-ASSOCIATED GRAFT-VERSUS-HOST DISEASE IN THE TREATMENT OF CANCER, Archives of Disease in Childhood, 71(6), 1994, pp. 532-533
Citations number
4
Categorie Soggetti
Pediatrics
Journal title
Archives of Disease in Childhood → ACNP
ISSN journal
00039888
Volume
71
Issue
6
Year of publication
1994
Pages
532 - 533
Database
ISI
SICI code
0003-9888(1994)71:6<532:PPITGD>2.0.ZU;2-6
Abstract
Experience of transfusion associated graft versus host disease (TA-GvH D) and current preventative policy in 22 UK children's cancer centres was established by questionnaire. Cellular blood products were irradia ted in all centres during bone marrow transplantation, but there was n o consensus for children receiving standard chemotherapy. Irradiation dose varied from 1500-5000 cGy and was below 2500 cGy in 12 units. Fiv e cases of TA-GvHD were identified; all five children died.