Conjugative transposon Tn916 from Enterococcus faecalis DS16 encodes t
etracycline resistance (Tet M) as well as determinants necessary for i
ts own movement. Determination of the nucleotide sequence of Tn916 has
been completed. The element is 18,032 bp in length and has an overall
G+C content of 38.8%. Twenty-four potential open reading frames (ORFs
) were identified based on sequence analysis. Similarities of the ORFs
to other known determinants, which were revealed by database searches
, are discussed. (C) 1994 Academic Press, Inc.