A three-year-old girl with epilepsia partialis continua involving the
left side of the face and the left arm and leg was followed-up by Tc-9
9m-HMPAO-SPECT in addition to EEG and CT. Increased regional cerebral
blood now was found in the right Rolandic area in the early stage of t
he disease, when the CT was normal and the EEG showed marked right hem
ispheric slowing. Seven months later severe hypoperfusion, extending t
o the right frontotemporal region, and localised hyperperfusion in the
right parietal area were observed by the (99)mTc-HMPAO-SPECT when CT
detected right hemispheric atrophy and EEG recorded severe epileptic a
ctivity, involving even the contralateral areas. The (99)mTc-HMPAO-SPE
CT proved to be useful for the follow-up of the dynamics of the diseas
e process.