CYTOGENETICAL AND FISH ANALYSIS ON A SALIVARY SEBACEOUS LYMPHADENOMA

Citation
J. Mark et al., CYTOGENETICAL AND FISH ANALYSIS ON A SALIVARY SEBACEOUS LYMPHADENOMA, Oncology Reports, 1(3), 1994, pp. 561-562
Citations number
6
Categorie Soggetti
Oncology
Journal title
ISSN journal
1021335X
Volume
1
Issue
3
Year of publication
1994
Pages
561 - 562
Database
ISI
SICI code
1021-335X(1994)1:3<561:CAFAOA>2.0.ZU;2-P
Abstract
Chromosomal studies of a cultured parotid sebaceous lymphadenoma showe d two abnormal cell groups, one with trisomy 9 (15% of the metaphases) and one with inconsistent structural deviations (10%). FISH analysis showed that the trisomic clone was actually larger (36%) than that rev ealed by chromosomal studies. The sebaceous lymphadenoma represents th e fourth type of benign salivary gland tumor to show clonal chromosoma l deviations.