The imaging accuracy of a catheter-based endo-luminal ultrasound syste
m was compared to traditional imaging techniques for surgical treatmen
t of urethral diverticula in 7 women and 1 man. At surgical repair the
urethra was catheterized directly with a 6.2F or 9F (12.5 or 20 MHz.)
catheter-based ultrasound transducer, generating a 360-degree transax
ial real-time image. The endo-luminal ultrasound images were compared
with preoperative voiding cystourethrography (7 patients), transvagina
l ultrasound examinations (3) and double balloon urethrograms (2). Sur
gical diverticulectomy was then done with endo-luminal ultrasound moni
toring. Intraoperatively, all diverticula were well visualized by endo
-luminal ultrasound, which demonstrated improved identification of the
size and orientation of urethral diverticula, sludge within the diver
ticula, the extent of periurethral inflammation, diverticular wall thi
ckness, and the distance between the diverticular wall and urethral lu
men. In 3 patients the urethral connections of the diverticula were ex
ceptionally well visualized. Comparison with traditional imaging revea
led 2 false-negative and 1 false-positive voiding cystourethrograms, 1
false-negative transvaginal ultrasound study and 1 false-negative dou
ble balloon urethrogram. Intraoperative monitoring of the urethra enab
led precise anatomical dissection, eliminated all diverticular compone
nts, and prevented inadvertent urethral and bladder neck injury. Ureth
ral endo-luminal ultrasound is a valuable new adjunct in the evaluatio
n of a variety of urethral abnormalities. This new ultrasound applicat
ion permits visualization of the precise size, location, orientation a
nd characteristics of urethral diverticula and surrounding tissues. Th
rough enhanced imaging, surgical repair is facilitated. Further applic
ation of this technique should increase the diagnostic accuracy of ure
thral imaging beyond radiographic techniques currently available.