Angiocentric lymphoma, which is the malignant counterpart of angiocent
ric immunoproliferative lesions, comprises a rare group of nonHodgkin'
s lymphomas of T-cell origin. It is characterized by marked invasion a
nd destruction of small vessels by lymphomatoid cells, predominantly i
n the lungs. The prognosis is poor and many patients die within severa
l months. To our knowledge primary involvement of the genitourinary tr
act has not been previously reported. We report a case of a solitary p
rimary angiocentric lymphoma of the kidney in a patient with the acqui
red immunodeficiency syndrome. Therapy consisted of nephrectomy withou
t adjuvant treatment. Histological characteristics as well as diagnost
ic and therapeutic options are discussed.