GROWTH-FACTOR REGULATION OF MDM-2 MESSENGER-RNA EXPRESSION

Authors
FEI ZL RIZZO MG BASERGA R
Citation
Zl. Fei et al., GROWTH-FACTOR REGULATION OF MDM-2 MESSENGER-RNA EXPRESSION, Oncology Reports, 1(4), 1994, pp. 695-698
Citations number
32
Categorie Soggetti
Oncology
Journal title
Oncology Reports → ACNP
ISSN journal
1021335X
Volume
1
Issue
4
Year of publication
1994
Pages
695 - 698
Database
ISI
SICI code
1021-335X(1994)1:4<695:GROMME>2.0.ZU;2-B
Abstract
We have investigated the growth factor regulation of mdm-2 mRNA levels in mouse embryo fibroblasts, whose growth is controlled by platelet-d erived growth factor (PDGF) and insulin-like growth factor I (IGF-I). We find that both growth factors up-regulate the expression of mdm-2 m RNA, independently of each other.