In this investigation the presence of oncogene-related sequences in am
phibian genomes was examined by means of Southern hybridization. Our s
tudies show presence of these sequences in urodele and anura amphibia.
In addition, it seems that copies of some cross-hybridized sequences
were increased in species with more DNA per haploid nucleus. This prov
ides evidence that the higher complexity of genomes in some amphibians
does correlate with duplication of structural genes.