Jp. Richer et al., ANATOMIC AND RADIOLOGIC BASES OF COMBINED TRANSPLANTATION OF LIVER AND SMALL-INTESTINE IN THE PIG, Surgical and radiologic anatomy, 16(3), 1994, pp. 245-251
Citations number
13
Categorie Soggetti
Surgery,"Radiology,Nuclear Medicine & Medical Imaging
In order to assess the tolerance induced by hepatic transplantation in
a multivisceral graft, a model of a transplant combining the liver an
d small intestine was developed in the pig, using animals of Large Whi
te Isogroup O, typed in the system of major incompatibility as ''Swine
lymphocyte antigen'' (SLA), whose weight varied from 30 to 40 kg. In
order to limit the duration of warm ischemia, dissection of the graft
was performed on the donor animal with respect for the following anato
mic features: - absence of intestinal attachment to the posterior pari
etal peritoneum, - anti-clockwise torsion of 360 degrees of the intest
ine around the superior mesenteric a. with the small intestine convolu
tions on the right and the colonic helix on the left. The bifid pancre
as follows this rotation and its resection must respect the vascularis
ation of the proximal small intestine; - the hepatic a. arises from a
common trunk with a gastrosplenic branch of the aorta between the crur
a of the diaphragm and travels sagittally from behind foward toward th
e liver pedicle, which it reaches ar the upper border of the duodenum;
- the hepatic a. and its branches are dorsal in relation to the porta
l vein; - the hepatic arterial distribution follows a right-left and a
ntero-posterior systematisation for the six hepatic lobes of this quad
ruped animal.