MAGNETIC-RESONANCE-IMAGING AS A DIAGNOSTI C METHOD FOR ASSESSING FUNCTION - NEW PROCEDURES FOR THE NONINVASIVE QUANTIFICATION OF CEREBRAL BLOOD-VOLUME AND BLOOD-FLOW

This paper presents a brief introduction to the current status of cere bral blood volume and blood flow imaging with magnetic resonance imagi ng (MRI) techniques. A new method for the quantitative assessment of r egional cerebral blood volume (rCBV) and regional cerebral blood flow (rCBF) on the basis of the indicator dilution theory is described and preliminary quantitative results from healthy volunteers are presented . The mean values for the rCBV are 8,27 +/- 1,85 ml/100 g for grey mat ter and 3,78 +/- 1,34 ml/100 g for white matter. The mean values for t he rCBF are 44,8 +/- 11,29 ml/min/100 g for the grey matter and 20,88 +/- 8,42 ml/min/100 g for the white matter. These results are in good agreement with PET results from the literature.