SKIN SIGNS OF SYSTEMIC-DISEASE - WHEN THE PROBLEM IS MORE THAN SKIN-DEEP

Authors
HOLMES CE MASSA MC
Citation
Ce. Holmes et Mc. Massa, SKIN SIGNS OF SYSTEMIC-DISEASE - WHEN THE PROBLEM IS MORE THAN SKIN-DEEP, Postgraduate medicine, 96(8), 1994, pp. 93
Citations number
32
Categorie Soggetti
Medicine, General & Internal
Journal title
Postgraduate medicine → ACNP
ISSN journal
00325481
Volume
96
Issue
8
Year of publication
1994
Database
ISI
SICI code
0032-5481(1994)96:8<93:SSOS-W>2.0.ZU;2-T
Abstract
The cutaneous manifestations of systemic diseases are diverse. In some cases, they are the first signs of an underlying disorder, such as Co wden's disease, dermatomyositis, and Lyme disease. Sister Mary Joseph' s nodule (metastatic involvement of the umbilicus) is an ominous sign of internal malignant disease. Drug-induced skin necrosis may result f rom therapy with coumarin (Coumadin, Panwarfin, Sofarin) or heparin.