R. Famularo et T. Fenton, EARLY DEVELOPMENTAL HISTORY AND PEDIATRIC POSTTRAUMATIC-STRESS-DISORDER, Archives of pediatrics & adolescent medicine, 148(10), 1994, pp. 1032-1038
Objective: To determine which factors from the early developmental his
tories of maltreated children are associated with the risk of developi
ng;posttraumatic stress disorder(PTSD). Design: Retrospective cohort a
nalytic study. Setting: A county juvenile/family court (not a criminal
court). Sample: The sample consisted of 117 severely maltreated child
ren, aged 5 to 12 years, whose maltreatment was so severe that they we
re removed from parental custody. Forty-one (35%) of these children me
t criteria of the Diagnostic and Statistical Manual of Mental Disorder
s, Revised Third Edition, for PTSD. Main Outcome Measures: Individual
developmental and temperament-independent variables were used to compa
re children with PTSD and the maltreated children who did not reach PT
SD inclusion criteria. The child's PTSD status was the primary depende
nt variable. Results: Variables representing the three factors from th
e early developmental history, along with markers for sex and race (bl
ack vs other), were entered into a logistic regression, with PTSD stat
us as the outcome variable. Indicators of five different types of chil
d maltreatment were also entered as predictors, to control for previou
sly discovered effects associated with the type of trauma suffered by
the children. This analysis disclosed that, while we controlled for th
e other predictors, one of the developmental factors remained statisti
cally significant, one was marginally significant (P = .07), and one m
ade no contribution toward predicting the probability of PTSD. Sex did
not make a significant contribution to the logistic model, but being
black continued to be associated with a lower probability of developin
g PTSD. Conclusions: We conclude that PTSD may be caused by factors di
scernible in the first year of life that leave a maltreated child vuln
erable to this disorder. These include birth weight less than 2.25 kg,
jaundice, vomiting, diarrhea, infections, sleep problems, frequent cr
ying, poor weight gain, fussiness, jumpiness, and distress when moved.
The seemingly protective effect of being black was an unexpected, alt
hough provocative, finding whose interpretation will require further i
nvestigation.