The increased risk of hemodialysis patients for infections sustained b
y hepatitis viruses is likely to extend to a newly discovered parenter
ally transmitted virus, HGBV-C/HGV, able to cause acute and chronic he
patitis. The aim of this study was to assess the prevalence and clinic
al relevance of this infection in Italian haemodialysis patients. Nine
teen of 100 patients (19%) on maintenance hemodialysis were viremic fo
r HGBV-C/HGV, and all of them were infected with a HGV-like genotype.
Eight of these patients were coinfected by hepatitis B or hepatitis C
viruses. A clinical picture of chronic hepatitis was not appreciable i
n patients with isolated HGV infection and the presence of HGV did not
appear to modify the clinical course of hepatitis B and hepatitis C i
nfections.