ELEVATION OF INTERLEUKIN-2 PRODUCTION IN PERIPHERAL-BLOOD LYMPHOCYTESBY RECOMBINANT HUMAN GRANULOCYTE-COLONY-STIMULATING FACTOR IN OVARIAN-CANCER PATIENTS DURING COMBINATION CHEMOTHERAPY

Authors
IMAIZUMI E KITA T ISHII K HIRATA J KIKUCHI Y NAGATA I
Citation
E. Imaizumi et al., ELEVATION OF INTERLEUKIN-2 PRODUCTION IN PERIPHERAL-BLOOD LYMPHOCYTESBY RECOMBINANT HUMAN GRANULOCYTE-COLONY-STIMULATING FACTOR IN OVARIAN-CANCER PATIENTS DURING COMBINATION CHEMOTHERAPY, Oncology Reports, 1(5), 1994, pp. 941-944
Citations number
17
Categorie Soggetti
Oncology
Journal title
Oncology Reports → ACNP
ISSN journal
1021335X
Volume
1
Issue
5
Year of publication
1994
Pages
941 - 944
Database
ISI
SICI code
1021-335X(1994)1:5<941:EOIPIP>2.0.ZU;2-5
Abstract
Interleukin-2 (IL-2) production and peripheral blood lymphocyte (PBL) subsets were measured in ovarian cancer patients who received cis-plat inum based chemotherapy with or without recombinant human granulocyte colony stimulating factor (rhG-CSF). Additional treatment with rhC-CSF resulted in significant elevation of IL-2 production and highly diffe rentiated natural killer (NK) cell counts, indicating that rhG-CSF may be helpful for enhancement of the cellular immunity in ovarian cancer patients.