J. Ryczek, A NEW METHOD OF SYNTHESIS OF 3-MONOSUBSTITUTED-2-THIOHYDANTOINS AND 3-MONSUBSTITUTED-2-HYDANTOINS, Polish Journal of Chemistry, 68(12), 1994, pp. 2599-2604
A new method of synthesis of 3-monosubstituted derivatives of 2-thiohy
dantoin and hydantoin in reaction of isothiocyanate or isocyanate glyc
in ethyl ester with primary aliphatic and aromatic amines has been des
cribed. Crude products were obtained with high yield and purity. The s
tructure of these compounds was confirmed by spectral methods.