SIZE - A PROGRAM TO DETERMINE THE SIZE OF NUCLEIC-ACID AND PROTEIN MOLECULES FROM GEL MOBILITIES

Authors
HEPBURN AG
Citation
Ag. Hepburn, SIZE - A PROGRAM TO DETERMINE THE SIZE OF NUCLEIC-ACID AND PROTEIN MOLECULES FROM GEL MOBILITIES, BioTechniques, 17(6), 1994, pp. 1140-1142
Citations number
2
Categorie Soggetti
Biochemical Research Methods
Journal title
BioTechniques → ACNP
ISSN journal
07366205
Volume
17
Issue
6
Year of publication
1994
Pages
1140 - 1142
Database
ISI
SICI code
0736-6205(1994)17:6<1140:S-APTD>2.0.ZU;2-X
Abstract
The relationship between fragment length and the reciprocal of mobilit y and the least-squares curve fitting analysis for this relationship h ave been combined into a user-friendly program for determining the siz e of unknown DNA fragments by reference to known standards. Protein si zes can be determined in the same way. The program offers an accurate, simple-to-use mechanism for sizing molecules that requires only an IB M(R)-compatible computer.