Jp. Mullooly et al., INFLUENZA VACCINATION PROGRAMS FOR ELDERLY PERSONS - COST-EFFECTIVENESS IN A HEALTH MAINTENANCE ORGANIZATION, Annals of internal medicine, 121(12), 1994, pp. 947-952
Objective: To estimate the cost-effectiveness and net medical care cos
ts of programs for annual influenza vaccinations for the elderly in a
health maintenance organization (HMO). Design: Population-based, case-
control study. Setting: The Northwest Region of Kaiser Permanente, a p
repaid group practice HMO in Portland, Oregon. Participants: Kaiser Pe
rmanente members 65 years of age and older who had at least 1 month of
HMO eligibility during any of nine influenza seasons in the 1980s. Me
asurements: The HMO's costs for providing medical care and conducting
Vaccination programs were estimated using accounting data. Results: 32
% of high-risk elderly persons and 22% of non-high-risk elderly person
s received influenza vaccinations. Aggregate vaccine effectiveness in
preventing pneumonia and influenza hospitalizations was 30% (95% CI, 1
7% to 42%) for high-risk and 40% (CI, 1% to 64%) for non-high-risk eld
erly persons. The net savings to the HMO per vaccination was $6.11 for
high-risk elderly persons and $1.10 for all elderly persons. The HMO
incurred a net cost of $4.82 per vaccination for non-high-risk elderly
persons. Conclusions: Influenza vaccination rates in this HMO were re
latively low for high-risk elderly persons. The medical care costs sav
ed by preventing pneumonia and influenza through Vaccination of high-r
isk elderly persons provide a compelling rationale to increase complia
nce with recommendations for annual influenza vaccination. Indirect be
nefits, such as prevention of suffering, incapacity, and lost wages, a
re likely to compensate for the small net cost of vaccinating non-high
risk elderly persons.