J. Shapiro et al., PREVENTION OF INFECTION IN A PATIENT WITH CHRONIC IDIOPATHIC NEUTROPENIA UNDERGOING CORONARY-BYPASS SURGERY WITH PERIOPERATIVE G-CSF, Australian and New Zealand journal of surgery, 66(12), 1996, pp. 841-842
The prevention of postoperative infection complications in a patient w
ith chronic idiopathic neutropenia treated with granulocyte colony sti
mulating factor (G-CSF) is reported. A 48-year-old woman who presented
with chronic idiopathic neutropenia causing life-long recurrent infec
tions, and postoperative suppurative wound infections, presented for e
lective coronary artery surgery. The patient was successfully treated
with G-CSF, resulting in a significantly higher neutrophil count and n
o infection complications in the peri-operative period. Peri-operative
G-CSF therapy in patients with chronic idiopathic neutropenia is effe
ctive in increasing the total neutrophil count, and decreasing infecti
on complications.