HIGH DOSAGE INTERMITTENT STEROID-THERAPY IN THE TREATMENT OF CHRONIC INTERSTITIAL PNEUMONIA IN AN INFANT - A CASE-REPORT

Chronic interstitial pneumonia (PIC) are rave in infants. We report a case of an infant who presented with a chronic interstitial pneumonia following an infection with a respiratory syncytial virus. The diagnos is was confirmed histologically (open lung biopsy). The failure of ora l steroid therapy (Prednisolone 2 mg/kg/day) led to the use of boluses of methylprednisone (30 mg/kg/day, daily for three days in three seri es one month apart). The treatment led to a progressive improvement an d thirty months after the last bolus the respiratory examination was n ormal as was the radiology. The efficacy of bolus steroid therapy obse rved by other authors should be confirmed in multicentre trials ruing surgical biopsy to precise the pulmonary lesions.