INFECTION BY MYCOBACTERIUM-AVIUM COMPLEX REVEALING A CYSTIC-FIBROSIS

We report a case of pulmonary infection by Mycobacterium avium complex revealing in a 21 years old patient a cystic fibrosis heterozygous fo r the delta F 508 deletion. The role of his bacteria in the lung infec tion is suggested by repeated isolation. This infection caused bronchi tis, hypoxemia and pulmonary nodules at CT scan. The clinical and radi ological signs improved after treatment with foul antibiotics whereas only clarithromycin showed in vitro activity. An obstructive disease d ue to allergic bronchopulmonary aspergillosis developped and was contr olled by steroid therapy.