The management of postpneumonectomy bronchopleural fistulae continues
to constitute a major therapeutic challenge. Refinements of surgical t
echniques have reduced the incidence of this dreaded complication alth
ough it cannot be totally prevented. Management remains controversial.
We report our recent experience of three patients with bronchopleural
fistulae following a right pneumonectomy, two for bronchogenic carcin
oma and another for non-tuberculous, suppurative lung disease. Our tre
atment of choice for these patients is, immediate pleural drainage tog
ether with parenteral broad spectrum antibiotics followed by endoscopi
c closure of the fistula with monomeric n-butyl-2-cyanoacrylate glue (
Histoacryl blue, B Braun, Melsungen, Germany). The pleural space is th
en irrigated with Povidone Iodine to sterility following which the clo
sed bronchial stump is reinforced following which the closed bronchial
stump is reinforced and the pleural space obliterated by decorticatio
n, omentopexy and by a tailored thoracoplasty. This cosmetically accep
table treatment produces minimal functional disability and is achieved
with minimal morbidity and mortality in these critically ill patients
.