Sa. Afanasev et al., CHANGES IN RHYTHMOINOTROPIC REACTIONS OF THE MYOCARDIUM IN CHRONIC ISCHEMIA - PATHOLOGY OR ADAPTATION, Bulletin of experimental biology and medicine, 117(5), 1994, pp. 452-454
Changes in the organization of the Ca+-transporting systems but not di
sturbances in the contractile apparatus of cardiomyocytes are shown to
occur in chronic coronary heart disease. During a certain stage of CH
D the change in rhythmoinotropic relations may reflect adaptive change
s induced by functioning of the myocardium under conditions of ischemi
a.