ANTITHROMBOGENIC EFFECT OF UROKINASE BOUND TO COLLAGEN SUBSTRATE WITHBIFUNCTIONAL ANTIBODIES

Authors
STEPANOVA IP TSYBULSKAYA MV DOMOGATSKII SP
Citation
Ip. Stepanova et al., ANTITHROMBOGENIC EFFECT OF UROKINASE BOUND TO COLLAGEN SUBSTRATE WITHBIFUNCTIONAL ANTIBODIES, Bulletin of experimental biology and medicine, 117(5), 1994, pp. 502-505
Citations number
5
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Bulletin of experimental biology and medicine → ACNP
ISSN journal
00074888
Volume
117
Issue
5
Year of publication
1994
Pages
502 - 505
Database
ISI
SICI code
0007-4888(1994)117:5<502:AEOUBT>2.0.ZU;2-3
Abstract
In vitro experiments simulating collagen-induced thrombogenesis in art eries damaged during angioplasty demonstrate a marked inhibitory effec t of surface-bound urokinase. In contrast to free urokinase, bound enz yme is more effective in preventing platelet aggregation on the collag en surface.