ANDROSTENEDIONE CONVERSION IN HUMAN PERIPHERAL-BLOOD LYMPHOCYTES

Authors
BERSHTEIN LM LARIONOV AA KRYUKOVA OG
Citation
Lm. Bershtein et al., ANDROSTENEDIONE CONVERSION IN HUMAN PERIPHERAL-BLOOD LYMPHOCYTES, Bulletin of experimental biology and medicine, 117(5), 1994, pp. 516-518
Citations number
13
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Bulletin of experimental biology and medicine → ACNP
ISSN journal
00074888
Volume
117
Issue
5
Year of publication
1994
Pages
516 - 518
Database
ISI
SICI code
0007-4888(1994)117:5<516:ACIHPL>2.0.ZU;2-K
Abstract
The ability of human peripheral blood lymphocytes to convert the andro genic steroid metabolite androstenedione diminishes in women over 45 y ears old or during menopause. In patients with breast cancer in menopa use the ability of lymphocytes to convert androstenedione is enhanced compared with the control. The intensity of conversion in circulating lymphocytes correlates with the blood concentration of sex steroids.