Lm. Nepomnyashchikh et al., INTRACELLULAR REORGANIZATION OF RAT CARDIOMYOCYTES FOLLOWING TRANSFERTO HIGH-LATITUDES, Bulletin of experimental biology and medicine, 117(5), 1994, pp. 539-544
It is shown that as soon as the Ist day after transfer to high latitud
es, the regenerative processes are suppressed in some cardiomyocytes,
this manifesting itself in lytic changes of the sarcoplasm and organel
les in the perinuclear zone. After flight in the middle latitudes morp
hological signs of disturbances in the processes of intracellular rege
neration are observed only toward the end of the experiment. Intracell
ular spatial reorganization of cardiomyocytes for transfer to high lat
itudes and for flight in the middle latitudes has a stereotypic patter
n and primarily manifests itself in an increase of the volume density
of myofibrils and a decrease of this parameter for mitochondria.