PROTECTIVE HEPATOTROPIC EFFECT OF PREPARATIONS FROM MYTILIDAE AND GINSENG IN ANIMALS GIVEN DIOCTYL PHTHALATE

It is shown that in a group of animals given dioctyl phthalate alone a ntipyrine metabolism is enhanced (the urine content of its metabolites rises), and the histological structure of the Liver is altered by the end of the experiment: the plasmalemma membranes, the granular endopl asmic reticulum, and mitochondria are destroyed, and fat deposits are observed in the disrupted zones of the mitochondria. In animals given dioctyl phthalate and adaptogens simultaneously antipyrine metabolism normalizes, and the morphological structure of the liver changes sligh tly, although it does not normalize.