ULTRASTRUCTURE OF ERYTHROCYTES DURING CALCIUM-INDUCED IN-VITRO AGING

Authors
SOROKOVOI VI MOCHENOVA NN NIKITINA GM
Citation
Vi. Sorokovoi et al., ULTRASTRUCTURE OF ERYTHROCYTES DURING CALCIUM-INDUCED IN-VITRO AGING, Bulletin of experimental biology and medicine, 117(5), 1994, pp. 558-561
Citations number
10
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Bulletin of experimental biology and medicine → ACNP
ISSN journal
00074888
Volume
117
Issue
5
Year of publication
1994
Pages
558 - 561
Database
ISI
SICI code
0007-4888(1994)117:5<558:UOEDCI>2.0.ZU;2-P
Abstract
Vesiculation of the plasmalemma followed by fragmentation to microvesi cles and formation of microspherocytes are shown to be the main phenom ena during aging in rat erythrocytes. In human erythrocytes microvesic ulation from the apexes of echinocyte spicules and hemolysis in echino cytes II-IV are predominant. Hemolysis, vesiculation, and microvesicul ation are observed in rabbit, and hemolysis and microvesiculation in c anine erythrocytes. An increased level of free fatty acids (about 30% per hour) in human and rat erythrocytes is also detected.