Mc. Sulavik et al., ANALYSIS OF THE GENETIC REQUIREMENTS FOR INDUCIBLE MULTIPLE-ANTIBIOTIC RESISTANCE-ASSOCIATED WITH THE MAR LOCUS IN ESCHERICHIA-COLI, Journal of bacteriology, 176(24), 1994, pp. 7754-7756
A series of novel genetic constructs derived from the marRAB operon wa
s used to determine the role of this gene cluster in salicylate induci
ble multiple-antibiotic resistance in Escherichia coli. Our findings i
ndicate that regulated antibiotic resistance associated with this locu
s requires only the products of marR and marA, without any neighboring
genes.