CYTOMEGALOVIRUS GLYCOPROTEIN B-SPECIFIC ANTIBODY ANALYSIS USING ELECTROCHEMILUMINESCENCE DETECTION-BASED TECHNIQUES

Authors
OHLIN M SILVESTRI M SUNDQVIST VA BORREBAECK CAK
Citation
M. Ohlin et al., CYTOMEGALOVIRUS GLYCOPROTEIN B-SPECIFIC ANTIBODY ANALYSIS USING ELECTROCHEMILUMINESCENCE DETECTION-BASED TECHNIQUES, Clinical and diagnostic laboratory immunology, 4(1), 1997, pp. 107-111
Citations number
27
Categorie Soggetti
Immunology,"Infectious Diseases","Medical Laboratory Technology",Microbiology
Journal title
Clinical and diagnostic laboratory immunology → ACNP
ISSN journal
1071412X
Volume
4
Issue
1
Year of publication
1997
Pages
107 - 111
Database
ISI
SICI code
1071-412X(1997)4:1<107:CGBAAU>2.0.ZU;2-7
Abstract
An electrochemiluminescence technique was used to develop versatile an d sensitive assay strategies for determination of seroreactivities aga inst biologically important cytomegalovirus neutralization epitopes ex pressed on glycoprotein B. Indirect binding assays showed wide linear assay ranges and revealed that serum samples diluted in parallel with a monoclonal antibody-based standard, simplifying quantitative analyti cal assessments.