Fetal anastomotic connections between the developing internal carotid
and basilar arterial systems are via the three presegmental arteries:
the otic artery, the hypoglossal artery, and the trigeminal artery. Af
ter formation of the posterior communicating artery from the caudal br
anch of the internal carotid artery, the presegmental arteries are gen
erally obliterated. Rarely, however, these primitive carotid-basilar a
nastomoses will persist into adult life, and may be detected as incide
ntal findings at the time of cerebral angiography during evaluation of
the patient with suspected cerebrovascular disease. In addition, pers
istence of such anastomoses may result in the coexistence of anterior
and posterior circulation symptoms, precipitating diagnostic confusion
. Two patients with symptoms and persistent hypoglossal artery undergo
ing carotid thromboendarterectomy are discussed, with emphasis on clin
ical presentation, diagnostic criteria and intraoperative management.