ON-SITE DIGITAL QUANTITATIVE CORONARY ANGIOGRAPHY - COMPARISON WITH VISUAL READINGS IN INTERVENTIONAL PROCEDURES

In order to review the morphological criterion for an interventional p rocedure, diameter stenosis (%DS) of 226 coronary lesions in 200 patie nts undergoing elective coronary angiography with an option for 'prima vista' angioplasty (pPTCA), was assessed on-site by both visual 'eye balling' (EB) and independent digital quantitative coronary angiograph y (DQCA) by means of an angiographic workstation. Compared to DQCA, EB overestimated the %DS between 50 and 80% and accounted for the majori ty of discrepancies with overestimation up to 45%. Concordant estimate s of %DS by both methods were observed in only 10 of the total of 226 stenotic segments; in 20 of 226 cases, EB underestimated %DS up to 20% . EB revealed a %DS greater than or equal to 60% in 166 stenoses (73.4 %), an estimate that led to subsequent pPTCA. However, only 119 (52.6% ) of these lesions had a %DS greater than or equal to 60% as assessed objectively by DQCA. With regard to the criterion for PTCA 47 of 166 p erformed pPTCA (28.3%) would not meet the indication criteria based on objective DQCA information. EB and DQCA (+/- 5%DS) had concordant res ults and criteria for pPTCA only in 103 of 166 coronary lesions (62.1% ). These results lead to the conclusion that, on-site and on-line DQCA by an independent cardiologist eliminates both under- and overestimat ion of stenoses as seen with EB. DQCA supports immediate decision-maki ng and appears necessary for reliable evaluation of coronary morpholog y in an interventional catheterization laboratory setting and may even tually ensure intraprocedural quality control.