F. Nezhat et al., LIFE-THREATENING HYPOTENSION AFTER VASOPRESSIN INJECTION DURING OPERATIVE LAPAROSCOPY, FOLLOWED BY UNEVENTFUL REPEAT LAPAROSCOPY, The Journal of the American Association of Gynecologic Laparoscopists, 2(1), 1994, pp. 83-86
Vasopressin may be associated with systemic hemodynamic changes, inclu
ding severe myocardial ischemia, even in healthy patients. A 36-year-o
ld woman underwent laparoscopy for the treatment of a uterine leiomyom
a. After intravascular injection of vasopressin, she experienced life-
threatening hypotension, and the procedure was subsequently aborted. A
fter she recovered, she underwent successful laparoscopy without the u
se of vasopressin, and no complications occurred. As endogenous vasopr
essin levels sometimes rise during laparoscopy, patients may become su
sceptible to the drug's effects, and appropriate precautions must be t
aken.