COMBINED PRESSURE CONTROL HIGH-FREQUENCY VENTILATION IN ADULT-RESPIRATORY-DISTRESS-SYNDROME AND SICKLE-CELL-ANEMIA

Acute chest syndrome complicating sickle cell anemia may progress to a dult respiratory distress syndrome despite appropriate therapy. Extra- alveolar air leaks may complicate the care of these patients as conven tional mechanical ventilation becomes increasingly difficult. We succe ssfully treated a child with sickle cell anemia, acute chest syndrome, adult respiratory distress syndrome, and severe extra-alveolar air le aks using a new combined mode ventilatory approach: pressure control w ith high-frequency ventilation.