NOT WATER, BUT FORMALIN, DISSOLVES URATE CRYSTALS IN TOPHACEOUS TISSUE SAMPLES

Authors
SIMKIN PA BASSETT JE LEE QP
Citation
Pa. Simkin et al., NOT WATER, BUT FORMALIN, DISSOLVES URATE CRYSTALS IN TOPHACEOUS TISSUE SAMPLES, Journal of rheumatology, 21(12), 1994, pp. 2320-2321
Citations number
13
Categorie Soggetti
Rheumatology
Journal title
Journal of rheumatology → ACNP
ISSN journal
0315162X
Volume
21
Issue
12
Year of publication
1994
Pages
2320 - 2321
Database
ISI
SICI code
0315-162X(1994)21:12<2320:NWBFDU>2.0.ZU;2-4
Abstract
Objective, To examine the relative solubility of urate crystals in wat er, formalin, and ethanol. Methods. Weighed aliquots of synthetic crys tals were incubated in each solvent for 72 h at 4 degrees C and were t hen examined by polarized microscopy. Results. Urate crystals were ins oluble in alcohol, sparingly soluble in water, and markedly soluble in formalin. Conclusion. The marked solubility of urate in formalin is c onsistent with formation of urate:formaldehyde addition products.