ELECTROCHEMICAL ACTIVATION OF BROMOTRIFLUOROMETHANE USING VARIOUS REACTIVE ELECTRODES - SYNTHETIC APPLICATIONS

We describe the application of the sacrificial anode process to the ac tivation of bromotrifluoromethane, using various metals as anode. The method provides the trifluoromethylation of carbonyl compounds, SO2, D MF and organic halides in yields almost as good as classical organic p rocedures, and in milder conditions. The nature of both the anode and the metallic ions which arise from it play a paramount role either in the formation/non-formation of trifluoromethyl organometallic intermed iates, or by modulating their basicity and reactivity.