SYNTHESIS OF 4-OXA-2-AZAPODOPHYLLOTOXIN, A NOVEL ANALOG OF THE ANTITUMOR LIGNAN PODOPHYLLOTOXIN

Authors
HITOTSUYANAGI Y ICHIHARA Y TAKEYA K ITOKAWA H
Citation
Y. Hitotsuyanagi et al., SYNTHESIS OF 4-OXA-2-AZAPODOPHYLLOTOXIN, A NOVEL ANALOG OF THE ANTITUMOR LIGNAN PODOPHYLLOTOXIN, Tetrahedron letters, 35(50), 1994, pp. 9401-9402
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
50
Year of publication
1994
Pages
9401 - 9402
Database
ISI
SICI code
0040-4039(1994)35:50<9401:SO4ANA>2.0.ZU;2-1
Abstract
4-Oxa-2-azapodophyllotoxin (5) has been synthesized from sesamol (6). 5 showed significant activity against adriamycin-resistant P-388 leuke mia cells.