EFFECT OF THE SUBSTITUENTS ON THE DIASTEREOSELECTIVITY IN THE REDUCTION OF CYCLOPROPYL KETONES

Authors
DELANGHE PHM LAUTENS M
Citation
Phm. Delanghe et M. Lautens, EFFECT OF THE SUBSTITUENTS ON THE DIASTEREOSELECTIVITY IN THE REDUCTION OF CYCLOPROPYL KETONES, Tetrahedron letters, 35(51), 1994, pp. 9513-9516
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
51
Year of publication
1994
Pages
9513 - 9516
Database
ISI
SICI code
0040-4039(1994)35:51<9513:EOTSOT>2.0.ZU;2-H
Abstract
The reduction of several cyclopropyl ketones with hydride reagents was studied. High diastereoselectivities (15 to 20 : 1) were obtained wit h cis-cyclopropyl ketones, while virtually no facial selectivity was o bserved for the trans-analogues.