A CONVENIENT PROTECTIVE METHOD FOR THE 7-AMINO FUNCTION ON A CEPHEM DERIVATIVE IN WITTIG VINYLATION

Authors
KATSURA Y ARATANI M
Citation
Y. Katsura et M. Aratani, A CONVENIENT PROTECTIVE METHOD FOR THE 7-AMINO FUNCTION ON A CEPHEM DERIVATIVE IN WITTIG VINYLATION, Tetrahedron letters, 35(51), 1994, pp. 9601-9604
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
51
Year of publication
1994
Pages
9601 - 9604
Database
ISI
SICI code
0040-4039(1994)35:51<9601:ACPMFT>2.0.ZU;2-I
Abstract
A novel preparative pathway for diphenylmethyl 7 beta-amino-3-vinylcep h-3-em-4-carboxylate from 3-chloromethyl derivative is described. As a convenient protecting group for the 7-amino function in a Wittig reac tion, six membered azine derivatives incorporating the 7-amino group w ere developed as a surrogate of conventional protecting groups.