SYNTHESIS OF 3-THIENYL SUBSTITUTED 2-PYRAZOLINES BY 1,3-DIPOLAR CYCLOADDITION

Authors
KRAYUSHKIN MM KALIK MA VOZNESENSKY SA
Citation
Mm. Krayushkin et al., SYNTHESIS OF 3-THIENYL SUBSTITUTED 2-PYRAZOLINES BY 1,3-DIPOLAR CYCLOADDITION, Russian chemical bulletin, 43(1), 1994, pp. 110-113
Citations number
12
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
43
Issue
1
Year of publication
1994
Pages
110 - 113
Database
ISI
SICI code
1066-5285(1994)43:1<110:SO3S2B>2.0.ZU;2-#
Abstract
1,3,5-Trisubstituted 3-thienylpyrazolines have been prepared in high y ields by the reaction of substituted N-(p-nitrophenyl)-3-thiophenecarb ohydrazonoyl chlorides with Et(3)N in CH2Cl2 in the presence of an exc ess of a monosubstituted olefin. The reaction probably occurs as 1,3-d ipolar cycloaddition of the corresponding 3-thiophenecarbonitrile imin es formed in situ at the double bond of the olefin.