THE EFFECT OF ORGASM ON PROSTATE-SPECIFIC ANTIGEN

To identify the effect of orgasm on serum prostate-specific antigen (P SA) levels, a prospective trial before and after orgasm was performed in 14 healthy colleagues aged 32-62 years (mean, 44.4 years) with no e vidence of prostatic disease. PSA determinations were performed on ser um samples obtained before and after orgasm. Significant changes in PS A levels after orgasm were found (P = 0.002, analysis of variance). We conclude that the impact of orgasm on PSA levels should be taken into account when the latter are used for the detection of prostatic disea se.