Because licensure of a chickenpox (varicella) vaccine is likely soon,
it is important to ascertain the age-specific incidence of chickenpox.
Increasing vaccine coverage and a resulting decrease in transmission
may result in an accumulation of susceptible adults, followed by a shi
ft of incidence into those older age groups in future years. Valid bas
eline age-specific incidence will make it possible to detect this phen
omenon. Two studies were conducted in Kentucky to assess age-specific
incidence of chickenpox. The first assessed chickenpox occurrence in t
wo consecutive school-year cohorts of children from a geographically r
epresentative sample of Kentucky primary schools. The second gathered
information from household members of those persons interviewed in the
Behavioral Risk Factor Surveillance System telephone survey. The age-
specific rates are remarkably similar between studies. Rates peak duri
ng the preschool and kindergarten years (ages 3-6). Approximately 20 p
ercent of children remain susceptible to chickenpox after age 8 in bot
h studies. The results from these two surveys will be valuable baselin
es for comparison with findings in incidence studies that will be perf
ormed after vaccine licensure.