BACTERIOLOGICAL STUDY OF ACUTE PURULENT R HINO-PHARYNGITIS IN CHILDREN - EPIDEMIOLOGIC 1993 SITUATION IN TOULOUSE COUNTRY

Bacteriological studies were performed on samples obtained from 300 ch ildren consulting for acute purulent rhinopharyngitis during the perio d from november 1992 to february 1993. The most frequent isolates were S. pneumoniae + H. influenzae (19,3% of the children), S. pneumoniae (18%), H. influenzae (13%), S. pneumoniae + H. influenzae + M. catarrh alis (6,6%), S. pneumoniae + M. catarrhalis (5%), H. influenzae + M. c atarrhalis (4,3%), S. aureus (4%), M. catarrhalis (2,6%), H. influenza e + S. pyogenes A (1,6%). S. pneumoniae strains (isolated from 49% of the children) belong to the serogroups 19 (28,4%), 6 (24,4%), 23 (23,6 %), 14 (11,4%), 15 (6,5%) et 3, 9, 10, 18, 21, 31 (5,7%). Penicillin r esistance concerned 15,6% of the strains (10,2% of intermediate suscep tibility, 5,4% resistant); they belonged to serogroup 23 and 14. Eryth romycin resistance concerned 50% of pneumococcal strains. H. influenza e strains (isolated from 45% of the children) were non capsulated (97, 7%). Ampicillin resistance was observed for 34% of the strains by beta -lactamase production and for 3,8% by another mechanism. Strains of M. catarrhalis (isolated from 19% of the children) were resistant to amp icillin by beta-lactamase production (96,5% of the strains).