Recent research indicates that approximately 60% of children diagnosed
with cancer in Britain are cured and as a result, about 1 in a 1000 o
f the general population will soon be survivors of childhood cancer. U
nfortunately some elements of the therapies which ore responsible for
this remarkable success are associated with serious complications, som
etimes decades after their administration. Therefore, a comprehensive
knowledge of the risks and benefits of different therapies will only b
e obtained by monitoring the health of survivors indefinitely. With su
ch therapeutic success, increasingly the composition of future treatme
nt protocols will be influenced by knowledge of the risks of long term
morbidity and mortality associated with past therapies. An awareness
of the long term risks of complications of treatment is also important
For estimating the future demand on the health services of this incre
asing proportion of the general population who together represent many
life years of care. This chapter reviews what is known concerning the
long term risks Of complications of different treatments. Appropriate
strategies For future clinical and epidemiological follow-up of the s
urvivor population are discussed and the need for indefinite follow-up
of the survivor population is emphasised.