THE REMOVAL OF HUMAN LEUKEMIA-CELLS FROM BLOOD USING INTERDIGITATED MICROELECTRODES

Citation
Ff. Becker et al., THE REMOVAL OF HUMAN LEUKEMIA-CELLS FROM BLOOD USING INTERDIGITATED MICROELECTRODES, Journal of physics. D, Applied physics, 27(12), 1994, pp. 2659-2662
Citations number
26
Categorie Soggetti
Physics, Applied
ISSN journal
00223727
Volume
27
Issue
12
Year of publication
1994
Pages
2659 - 2662
Database
ISI
SICI code
0022-3727(1994)27:12<2659:TROHLF>2.0.ZU;2-3
Abstract
An electroaffinity column containing an interdigitated microelectrode array was used to retain human leukaemia cells dielectrophoretically a nd thereby separate them from normal blood cells. The leukaemic cells could be subsequently released by removal of the dielectrophoretic fie ld and collected. This novel approach exploits the differential dielec tric properties of cells as a sorting criterion and has applications i n medicine, biotechnology and environmental settings.