The separation of persistent depression into meaningful and useful sub
categories, including major depression, dysthymia, recurrent brief dep
ression, and depressive personality disorder, is the subject of much d
ebate. Depressions can be grouped on the basis of their type and sever
ity of symptoms, aetiology, clinical course, or their association with
other psychiatric illnesses. Several investigators have conducted epi
demiologic and family studies to evaluate the prevalence of depressive
disorders, their diagnostic stability over time, and the amount of ov
erlap among the disorders. Although progress has been made toward a be
tter understanding of the different disorders, insufficient evidence e
xists to support the hypothesis that these disorders are separate and
distinct from one another. However, preliminary data suggest that depr
essive personality disorder is separate from the other disorders. Addi
tionally, several questions have been raised, particularly the extent
to which differentiation between the depressive disorders, specificall
y major depression and dysthymia, has an impact on treatment decisions
.