Objective-To test whether handedness is associated with a change in lo
ngevity.Design-Archival survey. Setting-British Isles. Subjects-All fi
rst class cricketers born before 1961 whose bowling hand was specified
(right, n = 5041; left, n = 1132) in a comprehensive encyclopaedia. M
ain outcome measures-Bowling hand and life span. Results-Regression an
alysis of the 5960 players born between 1840 and 1960 (3387 dead, 2573
alive) showed no significant relation between mortality and handednes
s (P = 0.3). Left handedness was, however, associated with an increase
d likelihood of death from unnatural causes (P = 0.03, log hazard 0.37
, 95% confidence interval 0.04 to 0.70). This effect was especially re
lated to deaths during warfare (P = 0.009, log hazard 0.53, 0.13 to 0.
92). Conclusion-Left handedness is not, in general, associated with an
increase in mortality.