Hepatitis A virus (HAV) is a major waterborne disease agent with world
wide distribution. The main transmission route of HAV is direct person
-to-person contact. However, hepatitis A (HA) outbreaks associated wit
h the consumption and use of fecally contaminated water were reported
from many countries. Studies on the environmental behavior of HAV were
feasible only after developing techniques for its cultivation and enu
meration in tissue culture. This study reviews data on the extent of H
AV prevalence and persistence in the environment and water. HA is high
ly prevalent in low socioeconomic populations as determined by seroepi
demiologic studies. HAV is excreted for long periods by infected indiv
iduals, but it is also shed by healthy persons. HAV has been detected
in concentrated wastewater and natural waters. However, in most cases
the natural waters were monitored for the presence of HAV after the oc
currence of HA outbreak. HAV persists for months at temperatures below
10 degrees C and for at least 1 month at ambient temperature (20 to 2
5 degrees C). Physical, biological, and chemical factors that influenc
e the survival of enteric viruses - such as temperature, pH, salt conc
entration, microbial activity, and humidity - have similar effects on
HAV. Drinking water treatment processes such as coagulation, high rate
filtration, and disinfection seem to be effective in removing HAV fro
m water.