Y. Gozal et al., BUPIVACAINE WOUND INFILTRATION IN THYROID-SURGERY REDUCES POSTOPERATIVE PAIN AND OPIOID DEMAND, Acta anaesthesiologica Scandinavica, 38(8), 1994, pp. 813-815
Control of postoperative pain is an important element in preventing th
e modification of the excitability of the dorsal horn neurons. We stud
ied the efficacy of bupivacaine 0.5% wound infiltration for postoperat
ive pain management following thyroid surgery. Forty consecutive ASA I
-II patients, scheduled for thyroidectomy, were assigned randomly to t
wo groups. Group I (n=20) consisted of patients receiving bupivacaine
0.5% (10 mi) wound infiltration at the end of surgery and group II (n=
20) included patients without infiltration. The patients did not know
whether the wound had been anaesthetized or not. All patients received
balanced inhalational anaesthesia, including fentanyl (a total dose o
f up to 4 mu g.kg(-1)). Postoperative pain medication included morphin
e IV or IM, as needed. Twenty-four hours after surgery the worst pain
was recorded using a Visual analogue scoring system, from 0 to 10. Twe
nty-four hour postoperative morphine requirement was recorded. Groups
did not differ in demographic data. Pain scores were significantly dif
ferent in the two groups. In group I, the mean pain score was 3.7+/-1.
6 compared with 6.9+/-1.7 in group II (P<0.05). Only six patients (30%
) in group I received opioids and only one of these (5%) had a pain sc
ore above 5. In comparison, 18 patients (90%) in group II received mor
phine during the first postoperative day. The local injection of bupiv
acaine corresponds to a block of the superficial branches of the cervi
cal plexus. This study demonstrated a simple, efficient and safe way t
o reduce pain perception following a thyroidectomy.