We report on a 23-year-old male patient with general weakness, subfebr
ile temperatures, and arthralgia. The first symptoms were observed som
e months after a severe cytomegalovirus mononucleosis-gastroenteritis.
High titers of cryoglobulins suggested an autoimmunological process.
This case is interesting because of the association between cytomegalo
virus infection and cryoglobulinemia. In conclusion, the differential
diagnosis of autoimmune disease should be considered in the course of
viral infections.