MEDIAL PREOPTIC ALPHA-2-ADRENOCEPTORS IN THE REGULATION OF SLEEP-WAKEFULNESS

Authors
RAMESH V KUMAR VM JOHN J MALLICK H
Citation
V. Ramesh et al., MEDIAL PREOPTIC ALPHA-2-ADRENOCEPTORS IN THE REGULATION OF SLEEP-WAKEFULNESS, Physiology & behavior, 57(1), 1995, pp. 171-175
Citations number
21
Categorie Soggetti
Behavioral Sciences",Physiology,"Behavioral Sciences",Physiology
Journal title
Physiology & behavior → ACNP
ISSN journal
00319384
Volume
57
Issue
1
Year of publication
1995
Pages
171 - 175
Database
ISI
SICI code
0031-9384(1995)57:1<171:MPAITR>2.0.ZU;2-2
Abstract
Adrenergic alpha(2) agonist (clonidine) and its antagonist (yohimbine) were locally applied to the medial preoptic area (mPOA), to find out the role of alpha(2) receptors at this brain region in the regulation of sleep-wakefulness. Clonidine produced arousal, whereas yohimbine in duced sleep in freely moving animals. Behavioural arousal produced by clonidine administration was accompanied by EEG synchronization. The a lpha(2) receptors as the probable site of action of externally applied norepinephrine (NE), is discussed.